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They are not for human or veterinary use, and they are not approved by the FDA for any medical purpose

[6] NAD+ augmentation may counteract age-related NAD+ loss caused by overactive NAD-consuming enzymes (such as the NADase CD38), thereby supporting mitochondrial maintenance and metabolic homeostasis

Cardiovascular complications: These may include increased heart rate, difficulty breathing, chest pain, high blood pressure, and heart failure

In addition, there has not been any reports of adverse effects associated with the intake of normal daily requirements of vitamin B12 during lactation

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