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Some patients benefit from starting B12 supplementation at the same time they begin semaglutide therapy, while others may only need it after 36 months of GLP-1 treatment

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Diets high in fruits and vegetables (some of which contain melatonin and related indolic compounds) are associated with better sleep in epidemiological studies, though causality is hard to prove

Vitamin D3 supplementation is particularly useful during colder months when natural sunlight exposure is limited