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In post-cholecystectomy patients, this slowdown of stomach emptying may feel more pronounced because the intestines are already dealing with constant bile exposure

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NPT4 is located at the apical side of renal tubules, and functions as an apical voltage-driven urate efflux transporter, also known as NPT4-Na + /phosphate co-transporter ( Function of NPT4 ( SLC17A3 ) NPT4 plays an important role in the urate excretion and operates functionally with basolateral organic anion transporters 1/3 (OAT1/OAT3) (Riches et al., 2009

Furthermore, we found that the expression of the p-NF-B p65 protein was upregulated in peroxynitrite-exposed SGNs compared with the untreated controls, and the pretreatment with ebselen significantly reduced it while the lack of GPX1 increased it (Figure 8C)

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