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Background Breast cancer (BC) is the most common cancer in the UK with around 55,200 diagnoses annually (Cancer Research UK, 2021)

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Restoration of GLP-1R activity enhances CaMKK2-AMPK signaling, resulting in reduced -secretase 1 (BACE1)-mediated cleavage of amyloid precursor protein ( APP ), increased microglial clearance of amyloid- (A ) , and improved memory in multiple transgenic AD models [269]

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Nature of cerebral functional defects and their effect on fitness to drive

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