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Comment: I am thrilled to announce this partnership extension with our long-standing partner BAT, said Zak Brown, chief executive of McLaren Racing

Reports presented to the press emphasised that Dutch smokers were still relatively unconcerned about smoking (ITC Project, 2010) and that more must be done, which led to headlines in the media such as Are the Dutch too soft on smokers?. In 2010 the NPTs goal of 20% smokers was not reached

UPLC Conditions: an UPLC-ESIMS/MS system (SHIMADZU Nexera X2 UPLC, Applied Biosystems QTRAP 4500) was employed for the analysis of samples

These effects were significant across sites, as determined by harmonic mean P -values that combined site-specific results

Health authorities and manufacturers both emphasize that heated tobacco products are designed as alternatives for adult smokers, not products for non-smokers or younger users