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Core mechanisms of mitochondrial metabolic reprogramming Supplying flexible fuel: metabolic plasticity and therapeutic resistance CRC cells exhibit pronounced metabolic plasticity, enabling dynamic switching between glycolysis and mitochondrial OXPHOS in response to fluctuations in oxygen, glucose, and other metabolic substrates, thereby adopting a hybrid metabolic phenotype [6]

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Too little vitamin D results in soft bones in children (rickets) and fragile, misshapen bones in adults (osteomalacia)

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