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An fMRI study in obese individuals also reported a normalised brain response to food cues when treated with the GLP1RA exenatide [125]

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However, given the associated risks of cardiovascular disease and various cancers, the benefits of these medications, such as better glycemic control, weight loss and improvement in cardiometabolic risk factors as well as other obesity complications, appear to outweigh the risks for most adults with obesity [143, 153]

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This move by New York set a major precedent, making it clear that peptide sales could no longer ignore age-related restrictions