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Additionally, SI treatment leads to SLC7A11-dependent downregulation of P53 ( Colorectal cancer stem cells (CCSC) significantly impact prognosis, chemotherapy resistance, and treatment outcomes in CRC

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6164 Empagliflozin increased glucose levels in patients with PBH more so than in a non-PBH surgical control group yet did not affect nadir glucose during a mixed meal tolerance test in one study 62 and reduced glucose excursions but not hypoglycemia in individuals with PBH in another study

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