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Endocrinology 146 , 25442550 (2005)

In summary, this study revealed that dysfunction of cellular transport of cytoplasmic FA to mitochondria plays a critical role in UA-induced cardiomyocyte injury and thereby promotes LVR development and identified CPT1B as the key factor influenced by UA

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A subsequent pilot study (n=12) comparing oral liposomal glutathione (500 mg twice daily for 2 weeks) found increases in GSH levels in whole blood, erythrocytes, and plasma, along with reductions in 8-isoprostane (a marker of oxidative stress) (Buonocore et al., Oxid Med Cell Longev, 2016) [16]