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Key findings relevant to injection site safety: Injection site reactions were not significantly higher in retatrutide groups compared to placebo The most common injection site reactions were transient redness and mild discomfort No participants discontinued due to injection site reactions The overall safety profile was consistent with other GLP-1 receptor agonists The more recent TRIUMPH-4 phase 3 trial confirmed these safety findings in a larger population

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( 1 ) While occasional difficulties happen to many men at some point, persistent ED is often a sign of an underlying health issue

Liu X, Cheng L, Huang L, Li M, Shen Q, Li D