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flexneri can secret relevant IpaH family E3 effectors to exploit the hosts ubiquitination system to promote the ubiquitination and subsequent degradation of key host proteins essential for ubiquitination-mediated antibacterial responses 42,44,46

Cytokines and ER stress are reported triggers of PDL1 (also known as CD274 ) expression in beta cells, which occurs in type 1 diabetes [37]

Footnotes 12 Abbreviations used: IUGR, intrauterine growth retardation

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