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This study design differs from the single-dose lean-rat experiment in species, dosing schedule, duration, and endpoint, and the ED 50 values from the two studies should not be treated as directly comparable or rank-ordered across studies

However, when glutathione stores are low, the liver cannot effectively detoxify this metabolite, leading to potential liver damage

As an antioxidant, it inhibits melanin synthesis by quenching free radicals rather than directly suppressing tyrosinase activity

For laboratory use only

Distinctive activation mechanism of GHSR GHSR adopts an active conformation in our structures, which is stabilized by the G i protein