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Phylogenetic analysis of APXs To analyze the evolutionary relationship between identified APX homologs, the phylogenetic tree was constructed by MEGA 6 using the Maximum Likelihood (ML) method with 1000 bootstraps (Figure 5)

Int J Radiat Oncol Biol Phys 84(1):e61-7, 2012

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One such MSIA, termed IGF-1 MSIA-SRM, has been developed for IGF-1 with improved protocols for disrupting the IGF-1/IGFBP complex and for monitoring the immunoassays efficiency from sample preparation to mass spectrometric detection