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Astrocytes mediate neuroinflammation by acting as key intermediaries between the CNS and immune system, expressing cytokine receptors for IL-1, IL-6, TNF-, and IFN-, enabling them to sense immune signals [95]

Vasquez-Vivar J, Martasek P, Whitsett J, Joseph J, Kalyanaraman B

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Clinical Evidence on Semaglutide Combined with Mental Health Medications Published clinical trials have not identified major contraindications between semaglutide and common antidepressants like sertraline, fluoxetine, or venlafaxine