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Beyond the observed increase in female lifespan, we show that pharmacologic blockade of IGF-1R signaling preserves, to various degrees, many aspects of healthspan, including neuromuscular function and endurance, and attenuates the age-related increase in diastolic dysfunction, systemic inflammation, and neoplasias in females

The result is what dermatologists describe as improved skin clarity and a more even complexion

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Conversely, several dysbiosis-associated genera showed notable enrichment: Anaerovorax was strongly increased, a genus associated with protein fermentation and potential toxic metabolite formation

Over the study period, urinary excretion of aluminum increased without affecting urinary excretion of the essential metals iron and copper