doi: 10.1101/2023.11.09.23298266 Pubmed Abstract CrossRef Google Scholar View reference in article 14 TrougakosIPTerposEAlexopoulosHPolitouMParaskevisDScorilasAet al
The substantial overlap in the indication to initiate GLP-1 receptor agonist and SGLT-2 inhibitor in people with diabetes enhances exchangeability and success of trial emulation.6162 Notwithstanding the similarities in their antihyperglycaemic properties, SGLT-2 inhibitors and GLP-1 receptor agonists do not share a similar neuropsychiatric profile
Pediatrics , 99(6), 804-807
They also found the GLP-1 receptor agonists led to a 14% reduction in the risk of cardiovascular death, non-fatal heart attack, and non-fatal stroke
Notably, the adverse effects caused by metformin therapy for adolescent patients with PCOS, especially gastrointestinal side effects, need to be a concern, as they may affect their quality of life and treatment adherence