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some mutations in these genes may cause complete inhibition of spermatogenesis ( NR5A1, DMRT1 , and TEX11 , cause azoospermia in men ( Qualitative defects in spermatogenesis are characterized by various parameters, including sperm morphology, motility, and DNA and chromatin integrity, and by various conditions, including oligozoospermia, asthenozoospermia, teratozoospermia, and oligoasthenoteratozoospermia (OAT)

Koga M, Serritella AV, Messmer MM, Hayashi-Takagi A, Hester LD, Snyder SH et al

Pathological astrocytes, when mixed with healthy neurones, can, on their own precipitate neuronal death, again indicating a leading role of astrocytes in pathophysiology of ALS

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