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Nicotine increases ventricular vulnerability to fibrillation in hearts with healed myocardial infarction

However, it is a known DNA mutagen, and this in turn could lead to carcinogenic effects

Cigarette consumption estimates for 71 countries from 1970 to 2015: systematic collection of comparable data to facilitate quasi-experimental evaluations of national and global tobacco control interventions

Whether you're tracking your own smoking history or trying to understand its impact, knowing how to calculate pack years is essential