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In another study Vacca et al., did a retrospective study and assessed mouse models using a human proximity score derived from metabolic phenotypes, liver histopathology and transcriptomic similarity to human liver data (302)

The same 62.5 / 12.5 / 12.5 / 12.5 split scales up at 15 and 20 units

The answer depends entirely on one number they probably did not check: the concentration printed on their vial

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