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Varicoceles result from: Genetic predisposition (familial clustering occurs) Anatomical factors (valve incompetence, venous angle) Body structure (left renal vein compressionnutcracker phenomenon) What studies actually show: A 2023 case-control study compared underwear preferences in 412 men with varicocele versus 400 controls
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Changes in SPARC level in our study were correlated with changes in circulating levels of decorin, which is a collagen-associated extracellular matrix proteoglycan that promotes the formation of bone matrix and calcium deposition to regulate bone morphogenesis [26]
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