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This vascular remodeling decreases elasticity, heightening peripheral resistance and blood pressure [186, 187]

Used to treat or prevent Vitamin C deficiency and for physician-directed antioxidant support

Professional medical evaluation

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The report was uncontrolled, unblinded, not randomized, had no comparator arm, used patient-reported outcomes rather than validated pain instruments, and did not publish dose, effect size, confidence intervals, p-values, or systematically collected adverse events limitations that severely constrain any clinical inference