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It exists in two forms: reduced (GSH) and oxidized (GSSG)

Oxidative Stress Oxidative stress occurs when there is an imbalance between ROS generation and antioxidant activity ( Figure 2B ) and is an initiating free radical that can result in the formation of other reactive species such as hydrogen peroxide (H 2 O 2 ), hydroxyl radical, and peroxynitrite ( 2 O 2 , a less destructive oxidant and signaling molecule

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Unlike many other antioxidants that we must consume through food, our bodies are designed to produce glutathione internally, primarily in the liver