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ET-1 reduces NO bioavailability and influences endothelial function directly by both reducing eNOS expression [64, 73] and activity, and by activating the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, a superoxide producing enzyme located in vascular cells and inflammatory cells such as macrophages [2, 67, 84]

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Media JT changes it's packaging of tobacco products to comply with the amended order of Ministry of Finance Japan Tobacco Inc.(JT)(TSE:2914) announces today that it will gradually change all of its packaging of tobacco products in Japan to comply with The Ministerial Ordinance for the Partial Amendment of Tobacco Business Act Enforcement Regulations (Order of Ministry of Finance No

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Heritage factory: In 1989, the building and all of its machinery was acquired by the Hellenic Parliament and listed as a historic monument