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The majority of trials (n=16) did not discriminate according to whether there was expressed motivation to quit smoking or not

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As the manufacturers of these nicotinamide vape products assert that nicotinamide is the main active ingredient but also claim to have pharmacological activity at nAChRs, the FDA can alternatively categorize these products as a drug and regulate them under the Federal Food, Drug, and Cosmetic Act (FDCA)

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