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Instead, side effects can be controlled if the doctor continuously monitors, and because it has fewer side effects than other sedative anesthetics, it is used as an injection for sedative endoscopy or anesthesia induction during surgery

In addition, exposure to tobacco smoke extract (TSE) exposure can cause human macrophages to release EVs (including exosomes and ectosomes), which contribute to the release of matrix metalloproteinase 14 (MMP14) and may contribute to emphysema [102, 103]

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The narrative around Grim Fandango is usually constructed with a tragic flair, since it ended up becoming the penultimate LucasArts adventure game, followed only by Escape From Monkey Island in 2000