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For example, the breakdown of nicotine and its metabolites might slow down the breakdown of testosterone in the body, which could have the effect of increasing testosterone levels in the blood

The available resultsas well as any further similar results that will appear in the foreseeable futureare inherently too imprecise to provide a quantitative estimate

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Dan Halem, MLBs chief legal counsel, said Manfred could penalize players at his discretion for breaking the new rules

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