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People with pre-existing mental health conditions particularly depression or anxiety disorders may experience more pronounced mood-related symptoms and should consider speaking with a healthcare provider before attempting cessation

I know a few of the other reviews suggest that maybe a topping of some kind has been used, but this is an attribute which eludes me

Morbidity and Mortality in People With Serious Mental Illness

In conducting nicotine experiments on pregnant humans the authors effectively ignored scores of animal studies finding that nicotine during pregnancy causes what the authors term "serious detrimental effects." As reviewers, three of the study's authors, including the lead author, were involved in producing a 2005 UK guidance advocating NRT use by pregnant smokers