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In the United States, about 70% of adults struggle with obesity or being overweight

PMID: 10950816 Ng FM, et al

Effects of GLP-1 receptor agonists on bone metabolism in humans Until recently, there were no randomized controlled trials assessing the effects of GLP-1Ra on bone metabolism during the weight loss phase using standard BMD measurement sites (i.e., lumbar spine and proximal femur) [71, 72]

Individuals consuming under 1,000 kcals/d likely function in a catabolic state and the protein-sparing effect of carbohydrates is lost