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The primary driver of smoking behavior is nicotinethe major addictive substance and primary reinforcer of continued smoking

Maeda I, Hayashi T, Sato KK, Koh H, Harita N, et al

Kunming, the capital of Yunnan Province in southern China, is situated in a major tobacco producing and consuming province with high economic dependence on tobacco, no smoke-free legislation, and comparatively lower public awareness of tobacco control

I wonder if Roy is less crazy because he had fewer skeletons in his closet for a "demon" to torment him with

From BATs website: KBio will explore new opportunities to develop its plant-based production system, which has the potential to offer greater speed, scale-up opportunity and thermostability