Considering that e-liquids can contain anywhere from 3mg/ml to over 50mg/ml of nicotine, a few licks from a spill or chewing on a leaky cartridge can quickly lead to a medical emergency
These leaks slow recovery and can cause life-threatening infections requiring emergency care
although to a lesser degree than standard cigarettes, electronic cigarettes lead to an important increase in soluble nicotinamide adenine dinucleotide phosphate oxidase 2-derived peptides and a concomitant decrease in nitric oxide bioavailability.85 Nonetheless, in human coronary endothelial cells, tobacco smoke, but not electronic cigarette aerosols, was shown to induce nuclear factor erythroid 2-related factor 2 oxidative stress sensing factor transcription.86 In another study, exposure of umbilical endothelial vein cells to electronic cigarette compounds induced cytotoxic pathways, inhibited cell proliferation and altered cellular morphology when compared with regular tobacco.87 An animal study suggested that electronic cigarettes could also hamper metabolic homeostasis
You can also use it on hard surfaces like furniture and walls to help remove smoke odors
More research on the long-term impacts of ENDS use on the cardiovascular system are needed, but short-term studies show harm
