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Insulin-like growth factor 1 dysregulation has been reported in many cancers including NSCLC (Scagliotti and Novello, 2012)

G., Yin, H

The prevalence of obesity in adults, defined as a body mass index of 30 or higher (calculated as weight in kilograms divided by height per square metre), has risen from 30% in 1999 to 42% in the US

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introduced Zr into a manganese porphyrin-based MOF (Mn-MOF) to construct a biocompatible nanosensitizer along with the capacity of GSH exhaustion-enhanced ferroptosis (Figure 5F) (Figure 5G), thus elevating Mn-MOF-induced ROS concentration, leading to the deactivation of GPX4 and ROS-enhanced ferroptosis