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In the European Union, where smoking cessation rates were not significantly impacted by a flavors ban 36 , tobacco companies had launched new products such as flavored inserts and cigarillos to discourage quitting among flavored cigarette users 37,38

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The Aztecs stuffed the dried leaves of the sacred plant into cane tubes or hollow reeds, while various groups in Mexico, Central America, and South America crushed tobacco leaves and rolled them in maize husks or leaves

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