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Whether GHK-Cu produces lasting skin changes, whether tolerance develops, and whether long-term copper exposure in skin has adverse effects are unanswered questions

They address different biological layers of the same aging process

From a safety or side effect profile, I think the bigger concern is the side effect profile. The GLP-1s do have nausea and vomiting or gastrointestinal side effects, he said, which are usually more pronounced in the first month or two of therapy

These symptoms usually diminish over weeks to months as your body adapts

However, no controlled study has examined this combination in any species