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Daly, Helga Refsum et al., Plasma Homocysteine as a Risk Factor for Vascular Disease: The European Concerted Action Project, Journal of the American Medical Association, 1997;277:177581

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Throughout the entire 20th century, about 100 million people died earlier than they would have because of smoking

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People who use the drug regularly have a higher risk for heart attack, stroke, and other heart disease, according to a large population-based study published in the Journal of the American Heart Association