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Nitro fatty acids Nitro-fatty acids (NO 2 -FAs) are endogenous signalling mediators with strong anti-fibrotic and anti-inflammatory activities [286], able to promote NRF2 activation through the interaction and reversible post-translational modification of C273 and C288 present in the stress sensing domain (IVR) of KEAP1 [287]

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New research suggests the amount of weight patients lose after starting these medications could strongly influence their future risk of serious obesity-related diseases

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