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[2] The symptoms of genital herpes can manifest as a primary or recurrent infection, and they can include: A cluster of small, fluid blisters that can be itchy or painful The blisters can progress into sores and scabs before healing Intense itching or tingling in the affected area before the blisters develop The blisters typically appear on the genitals, anus, or groin Painful or burning sensation while you urinate Flu-like symptoms It is also one of the most common sexually transmitted infections and due to associated physical and psychological effects, it constitutes a considerable and very often underestimated medical problem