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Relapse Prevention: Prepare patients for potential relapse scenarios and develop strategies to prevent them

The central nicotinic cholinergic receptors, namely the low affinity 7 and the high affinity 42 nicotinic receptors located in the ventral tegmental area (VTA), are stimulated by nicotine resulting in a rapid release of dopamine in the nucleus accumbens, mediating the rewarding and reinforcing effects of nicotine (25) (Figure 1)

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Contact your GP or visit the NHS website to find local services that can offer personalised cessation advice and support