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Currently, the FDAapproved medications to treat AUD, that is, disulfiram, naltrexone and acamprosate, reduce drinking through three different mechanisms of action: (i) unpleasant effects when consuming alcohol, (ii) reduced rewarding/reinforcing effects of alcohol and (iii) reduced negative state when abstinent

10.1016/j.cell.2013.04.023 49 Czystowska-KuzmiczM.SosnowskaA.NowisD.RamjiK.SzajnikM.Chlebowska-TuzJ.et al

359 Under the treatment of electrohydrodynamic jetting, the OEG macromer polymerized and covalently interacted with the lysine residues from albumin, giving nanoparticles at an average size of 115 nm

This road is often long, and many promising ferroptosis markers remain bottlenecked in preclinical stages due to limited specificity or insufficient validation data

doi:10.1371/journal.pone.0272299