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Inhaling sends massive nicotine doses directly to the bloodstream

In people with heart disease, short-term exposure has been linked to heart attacks and arrhythmias

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This not only promotes inflammation but also accelerates the uptake of Oxidised LDL (low-density lipoprotein) cholesterol by immune cells, transforming them into foam cells- a sign of the formation of early atherosclerotic plaque

Inflammation and Immune Response : Smoking-induced dysbiosis can trigger an immune response, leading to inflammation in the gut lining