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9.6 Probiotics in obesity and cardiometabolic health Among the multiple factors driving the modern escalation of obesity, the most prominent are an inherited genetic susceptibility and a sustained energy imbalance, defined by a chronic excess of caloric intake relative to energy expenditure (412)

Calculations were implemented in R (v.4.3.0) using the package Orthologr 58

Winzell MS, and Ahren B

Hyperprolactinemia is associated with insulin resistance which improves with dopamine agonist therapy which might be related to the therapy associated weight loss and an activation of insulin signaling (5962)

According to Rafael Olartecoechea from Vive Ageless Weight Loss Center, combining tirzepatide with a healthy lifestyle can accelerate results, although its important to approach weight loss sustainably