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doi: 10.1038/s41467-019-09915-2 63 HonoratoL.BonillaJ

Rarely, and almost exclusively from injections rather than oral supplements

Despite this, a substantial body of pre-clinical and limited clinical research has mapped DSIPs pharmacological effects across multiple systems, identifying several probable mechanistic axes including NMDA receptor modulation, adrenergic system regulation, MAPK/ERK cascade interaction, and mitochondrial respiration effects while acknowledging that the existence of an undiscovered DSIP-like endogenous peptide(s) may account for part of the DSIP-like immunoreactivity observed in tissue distribution studies

Chicago stem cell therapy and regenerative medicine reports that rehabilitation protocols after PRP injection consist of 4 phases and are over 9 weeks following the procedure 49 ( Figure 2 )

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