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Confusion of the large hazards of smoking with the smaller hazards of most other exposures Lets consider one of the statements made by the British American Tobacco, a global multi-national cigarette manufacturing, in response to requests made by the US Congress in 2003 (Waxman, 2003) about their belief of the causal role of cigarette smoking: that causes of lung cancer, chronic obstructive pulmonary disease, and cardiovascular diseases are complex, and the mechanism of causation, as well as the possible role of any cigarette smoke constituent in causation, have not been scientifically established (Waxman, 2003)