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Effects linked to flavor restrictions including impacts on sales trends, use data, and attempts by industry to avoid these restrictions compellingly illustrate the need for strong flavor restriction policies that have few or no loopholes

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Some of these additives, combined with naturally occurring compounds in tobacco, can contribute to cancer-causing substances

Compliance with the 180-Day Statutory Maximum Evaluation Period The evaluation system needs to routinely meet the statutory 180-day deadline and therefore impose reasonable burdens on both applicants and evaluators