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Additionally, the increase in microvascular blood flow in muscles contributes to reduced intramuscular fat accumulation and alleviation of myosteatosis, while AMPK pathway-mediated increased fat oxidation supports the mobilization of intramuscular fat, allowing for improvements in energy metabolism and reduction of fat within muscle tissue [39]

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There also may not be enough information yet for groups that scientists are just now beginning to study in clinical trials like adolescents with type 2 diabetes or obesity, though the FDA has already approved several GLP-1 agonists for these groups (14,15)