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[56] Both diacetyl and acetyl-propionyl have been found in concentrations above those recommended by the US National Institute for Occupational Safety and Health

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Yet believing vaping is as dangerous as smoking does not appear to stop experimentation

Sample size calculation From a previous pilot study, we found that the C max least square mean of smoking subjects can reach values around 1314 ng/mL nicotine in plasma and coefficient of variation (CVs) between 40 and 60% among the different arms (data not shown)