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IL-4 targets mast cells (MCs) to expand in the intestine, which increases intestinal permeability and induces inflammatory response in sensitized mice (Leyva-Castillo et al., 2019)

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M., Ajithkumar, A

In a prospective cohort study involving Korean patients with various degrees of CKD, smoking was associated with a significantly higher risk of worsening kidney function, particularly in patients with estimated glomerular filtration rate (eGFR) values below 45 ml/min and proteinuria (more than 1 g/day)