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Anti-Inflammatory Action BPC-157 lowers the production of pro-inflammatory cytokines (ex

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Morrison, M., et al

Phil Hieters lab used this system to test two known human FEN1 inhibitors: PTPD (a N-hydroxyurea-based compound) and a derivative of NSC-13755, while both compounds inhibited growth of a humanized FEN1 yeast strain in the presence of MMS, only PTPD was a potent, specific inhibitor of hFEN1