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N Engl J Med 334(3):150154 Chalon S et al (2000) Nicotine impairs endothelium-dependent dilatation in human veins in vivo

People with Crohns disease who smoke have an increased number of relapses (flare-ups) and repeat surgeries, as well as a greater need for aggressive treatment and treatment with drugs known as immunosuppressants. Now, TobaccoInAustralia.org claims that, for those with reduced nicotine tolerance, cigarettes can make you poop

He started believing in his own publicity

Cardiovascular Disease People with diabetes already face an elevated risk of heart disease and stroke

(The widely used term misuse carries a similar meaning.) The DSM and ICD criteria differ somewhat, with the emphasis being on negative social consequences of substance use in DSM-IV, and on adverse physical and psychological consequences in ICD-10