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Most data reported in this review are from phase 3 clinical trials

There were no cases of vomiting and no treatment discontinuations because of gastrointestinal issues, even among participants receiving the maximum effective dose

Probiotics found in this supplement may also promote overall gut health by building up beneficial bacteria in the microbiome

[1] [13] Symptoms suggestive of diabetic ketoacidosis develop, including persistent vomiting, abdominal pain, rapid breathing, fruity-smelling breath, or confusion (though this is rare with type 2 diabetes and not specifically associated with GLP-1 receptor agonists)

The intestinal discoloration may be diffuse or patterned (as seen here) and vary in intensity from segment to segment