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Du Plessis, S

Remarkably, there is evidence that GLP-1 agonists can enhance left ventricular ejection fraction, inotropy, coronary blood flow, cardiac output, and vascular endothelial function because of their cardiovascular effects and decrease overall cardiovascular event risks

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Nrf2 interferes with the escape from cell death by interaction with other signaling pathways such as suppression of proapoptotic Jun Nterminal kinases (JNKs) (Elsby et al